Signaling pathway

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Glucagon (PT1696) mouse mAb

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Article Number: PH0307
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Glucagon
Application: IHC, IF, ELISA
Reactivity : Human,Mouse,Rat,
MW(CalcμLated) : 20 kD
Host Species: Mouse
Isotype : IgG2b, Kappa

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:200-400; IF 1:50-200; ELISA 1:500-5000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PT1696

Antigen & Target Information

Specificity : This antibody detects endogenous levels of Glucagon protein.
Gene name : GCG
Protein Name : Glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide (GRPP); Oxyntomodulin (OXM) (OXY); Glucagon; Glucagon-like peptide 1 (GLP-1) (Incretin hormone); Glucagon-like peptide 1(7-37) (GLP-1(7-37)); Glucagon-like peptide 1(7-36) (GLP-1(7-36)); Glucagon-like peptide 2 (GLP-2)]
Alias : GCG;Glucagon;

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasmic

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