Signaling pathway

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LRBA Polyclonal Antibody

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Article Number: PG7890
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: LRBA
Application: IHC,IF
Reactivity : Human,Mouse
MW(Observed) : 314 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:50-300; IF 1:50-200
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : LRBA Polyclonal Antibody detects endogenous levels of protein.
Gene name : LRBA BGL CDC4L LBA
Protein Name : Lipopolysaccharide-responsive and beige-like anchor protein (Beige-like protein) (CDC4-like protein)

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],

Cell localization : Cell membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . Golgi apparatus, trans-Golgi network membrane ; Single-pass membrane protein . Lysosome membrane ; Single-pass membrane protein .

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