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MLC-2 Polyclonal Antibody

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Article Number: PD4857
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: MLC-2
Application: IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 20 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : MLC-2 Polyclonal Antibody detects endogenous levels of MLC-2 protein.
Gene name : MYL12A
Protein Name : Myosin regulatory light chain 12A
Alias : MYL12A;MLCB;MRLC3;RLC;Myosin regulatory light chain 12A;MLC-2B;Myosin RLC;Myosin regulatory light chain 2;nonsarcomeric;Myosin regulatory light chain MRLC3;MYL12B;MRLC2;MYLC2B;Myosin regulatory light chain 12B;MLC-2A;MLC-2;M

Database connection:

Background:

This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.[provided by RefSeq, Dec 2014],

Cell localization : stress fiber, cytosol, brush border, myosin complex, myosin II complex, Z disc, apical part of cell, extracellular exosome,

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