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Article Number: PG5878
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Target: FILA
Application: IHC,IF
Reactivity : Human,Mouse
MW(Observed) : 446 kD
Host Species: Rabbit
Isotype : IgG
隐藏域元素占位
Detailed Information
Recommended dilution ratio : IHC 1:50-300; IF 1:50-200
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal
Antigen & Target Information
Specificity : FILA Polyclonal Antibody detects endogenous levels of protein.
Gene name : FLG
Protein Name : Filaggrin
Background:
The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.[provided by RefSeq, Dec 2009],


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