Signaling pathway

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UFD2 Polyclonal Antibody

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Article Number: PD3105
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: UFD2
Application: IHC, IF, ELISA
Reactivity : Human,Mouse
MW(CalcμLated) : 146 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : UFD2 Polyclonal Antibody detects endogenous levels of UFD2 protein.
Gene name : UBE4B
Protein Name : Ubiquitin conjugation factor E4 B
Alias : UBE4B;HDNB1;KIAA0684;UFD2;Ubiquitin conjugation factor E4 B;Homozygously deleted in neuroblastoma 1;Ubiquitin fusion degradation protein 2

Database connection:

Organism

Gene ID

SwissProt

Background:

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasm . Nucleus .

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