Signaling pathway

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Akt3 Monoclonal Antibody

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Article Number: PH1853
Delivery time: 一周
Price: 100 μL/2200

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : Affinity purification
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal

Antigen & Target Information

Specificity : Akt3 Monoclonal Antibody detects endogenous levels of Akt3 protein.
Gene name : AKT3
Protein Name : RAC-gamma serine/threonine-protein kinase
Alias : AKT3;PKBG;RAC-gamma serine/threonine-protein kinase;Protein kinase Akt-3;Protein kinase B gamma;PKB gamma;RAC-PK-gamma;STK-2

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008],

Cell localization : Nucleus . Cytoplasm . Membrane ; Peripheral membrane protein . Membrane-associated after cell stimulation leading to its translocation.

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