Signaling pathway

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EDEM1 Polyclonal Antibody

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Article Number: PG8010
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: EDEM1
Application: WB, ELISA
Reactivity : Human,Mouse
MW(Observed) : 72 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:5000-20000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : EDEM1 Polyclonal Antibody detects endogenous levels of protein.
Gene name : EDEM1 EDEM KIAA0212
Protein Name : ER degradation-enhancing alpha-mannosidase-like 1

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

function:Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. It lacks mannosidase activity.,similarity:Belongs to the glycosyl hydrolase 47 family.,subunit:Interacts with DERL2 and DERL3.,

Cell localization : Endoplasmic reticulum membrane ; Single-pass type II membrane protein .

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