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Article Number: PH1112
Delivery time: 一周
Price: 100 μL/2200
Category:
Target: Lamin B2
Application: World Bank
Reactivity : Human,Mouse
MW(Observed) : 68 kD
Host Species: Mouse
隐藏域元素占位
Detailed Information
Recommended dilution ratio : WB 1:500
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Antigen & Target Information
Specificity : This antibody detects endogenous levels of Lamin B2 and does not cross-react with related proteins.
Gene name : Lamin B2
Alias : LAMB 2;LAMB2;Lamin-B2;LMN 2;LMN B2;LMN2;LMNB 2;LMNB2;LMNB2_HUMAN;MGC2721;RGD1563803.
Background:
lamin B2(LMNB2) Homo sapiens This gene encodes a B type nuclear lamin. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Mutations in this gene are associated with acquired partial lipodystrophy. [provided by RefSeq, May 2012],


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