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Article Number: PA0513
Delivery time: 两个月
Price: 100ug/2200
Target: CD314/NKG2D
Application: ELISA
Reactivity : Human
隐藏域元素占位
Detailed Information
Recommended dilution ratio : ELISA 1:5000-100000
Compose : Phosphate-buffered solution
Source : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification process : Recombinant Expression and Affinity purified
Storage : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration : Please check the information on the tube
Clonality : Monoclonal
Clone Number : PN0146
Antigen & Target Information
Specificity : This recombinant monoclonal antibody can detects endogenous levels of CD314/NKG2D protein.
Gene name : KLRK1 D12S2489E NKG2D
Protein Name : Tumor necrosis factor receptor superfamily member 4 (ACT35 antigen) (OX40L receptor) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD antigen CD134)
Alias : ACT 35 antibody; ACT35 antibody; ACT35 antigen antibody; ATC35 antigen antibody; CD 134 antibody; CD134 antibody; CD134 antigen antibody; IMD16 antibody; Lymphoid activation antigen ACT35 antibody; OX 40 antibody; OX40 antibody; OX40 antigen antibody; OX40 cell surface antigen antibody; OX40 homologue antibody; OX40L receptor antibody; TAX transcriptionally activated glycoprotein 1 receptor antibody; TAX transcriptionally-activated glycoprotein 1 receptor antibody; TNF receptor superfamily member 4 antibody; TNFRSF 4 antibody; TNFRSF4 antibody; TNR4_HUMAN antibody; Tumor necrosis factor receptor superfamily member 4 antibody; Txgp 1l antibody; Txgp1 antibody; Txgp1l antibody
Background:
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of


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