Signaling pathway

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CD325 (PN0272) Nb-FC recombinant antibody

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Article Number: PA0412
Delivery time: 两个月
Price: 100ug/2200
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Target: CD1A
Application: FC, ELISA
Reactivity : Human

隐藏域元素占位

Detailed Information

Recommended dilution ratio : ELISA 1:5000-100000
Compose : Phosphate-buffered solution
Source : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification process : Recombinant Expression and Affinity purified
Storage : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration : Please check the information on the tube
Clonality : Monoclonal
Clone Number : PN0123

Antigen & Target Information

Specificity : This recombinant monoclonal antibody can detects endogenous levels of CD1A protein.
Gene name : CD1A
Protein Name : Cadherin-2 (CDw325) (Neural cadherin) (N-cadherin) (CD antigen CD325)
Alias : CADH2_HUMAN antibody; Cadherin 2 antibody; Cadherin 2 N-cadherin neuronal antibody; Cadherin 2 type 1 antibody; Cadherin 2 type 1 N-cadherin neuronal antibody; Cadherin 2; type 1; N-cadherin; neuronal; antibody; Cadherin-2 antibody; Cadherin2 antibody; Calcium-dependent adhesion protein neuronal antibody; CD325 antibody; CD325 antigen antibody; CDH2 antibody; CDHN antibody; CDw325 antibody; CDw325 antigen antibody; N-cadherin 1 antibody; N-cadherin antibody; NCAD antibody; Neural cadherin antibody; OTTHUMP00000066304 antibody; OTTHUMP00000067378 antibody; CD325 nanobody;

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded byThis gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

Cell localization : Cell membrane ; Single-pass type I membrane protein . Membrane raft ; Single-pass type I membrane protein . Endosome membrane ; Single-pass type I membrane protein . Subject to intracellular trafficking between the cell membrane and endosomes (PubMed:11231314). Localizes to cell surface lipid rafts (PubMed:18178838). .

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