Signaling pathway

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IL-2 (PN0546) Nb-FC recombinant antibody

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Article Number: PA0301
Delivery time: 两个月
Price: 100ug/2200
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Target: CD38
Application: ELISA
Reactivity : Human

隐藏域元素占位

Detailed Information

Recommended dilution ratio : ELISA 1:5000-100000
Compose : Phosphate-buffered solution
Source : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification process : Recombinant Expression and Affinity purified
Storage : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration : Please check the information on the tube
Clonality : Monoclonal
Clone Number : PN0602

Antigen & Target Information

Specificity : This recombinant monoclonal antibody can detects endogenous levels of CD38 protein.
Gene name : CD38
Protein Name : Interleukin-2
Alias : IL2;Interleukin-2;IL-2;T-cell growth factor;TCGF;Aldesleukin;IL-2 nanobody;

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded byThis gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein.This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Cell localization : Membrane; Single-pass type II membrane protein.

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