Signaling pathway

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VGLUT1 Rabbit mAb

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Article Number: PL0589
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: VGLUT1
Application: WB, IHC, IF, IP, ELISA
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 62 kD
MW(Observed) : 62 kD
Host Species: Rabbit
Isotype : IgG, Kappa

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein A
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PT1164R

Antigen & Target Information

Specificity : Endogenous
Gene name : SLC17A7 BNPI VGLUT1
Protein Name : Vesicular glutamate transporter 1
Alias : VGLU1; Vesicular glutamate transporter 1; VGluT1; Brain-specific Na⁺-dependent inorganic phosphate cotransporter; Solute carrier family 17 member 7;

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family. [provided by RefSeq, Jul 2008],

Cell localization : Function:Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.,similarity:Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.,tissue specificity:Expressed in several regions of the brain including amygdala, cerebellum, cerebral cortex, hippocampus, frontal lobe, medulla, occipital lobe, putamen and temporal lobe.,

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