Signaling pathway

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AGTR1 Polyclonal Antibody

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Article Number: PD1998
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: AGTR1
Application: WB, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 41 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:10000-20000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : This antibody detects endogenous levels of AGTR1.
Gene name : AGTR1 AGTR1A AGTR1B AT2R1 AT2R1B
Protein Name : Type-1 angiotensin II receptor (AT1AR) (AT1BR) (Angiotensin II type-1 receptor) (AT1)
Alias : AGTR1;AGTR1A;AGTR1B;AT2R1;AT2R1B;Type-1 angiotensin II receptor;AT1AR;AT1BR;Angiotensin II type-1 receptor;AT1

Database connection:

Organism

Gene ID

SwissProt

Background:

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012],

Cell localization : Cell membrane ; Multi-pass membrane protein .

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