Signaling pathway

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GCM2 Polyclonal Antibody

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Article Number: PD2046
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: GCM2
Application: WB, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 56 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:10000-20000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : GCM2 Polyclonal Antibody detects endogenous levels of GCM2
Gene name : GCM2
Protein Name : GCM2
Alias : Chorion-specific transcription factor GCMb;hGCMb;GCM motif protein 2;Glial cells missing homolog 2;

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene is a homolog of the Drosophila glial cells missing gene, which is thought to act as a binary switch between neuronal and glial cell determination. The protein encoded by this gene contains a conserved N-terminal GCM motif that has DNA-binding activity. The protein is a transcription factor that acts as a master regulator of parathyroid development. It has been suggested that this transcription factor might mediate the effect of calcium on parathyroid hormone expression and secretion in parathyroid cells. Mutations in this gene are associated with hypoparathyroidism. [provided by RefSeq, Jul 2008],

Cell localization : Nucleus .

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