Signaling pathway

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CD123 (PN0612) Nb-FC recombinant antibody

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Article Number: PA0658
Delivery time: 现货
Price: 100ug/2200
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Target: CD10
Application: ELISA, FC
Reactivity : Human

隐藏域元素占位

Detailed Information

Recommended dilution ratio : ELISA 1:5000-100000; Flow Cyt 1-2μg/Test
Compose : Phosphate-buffered solution
Source : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification process : Recombinant Expression and Affinity purified
Storage : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration : Please check the information on the tube
Clonality : Monoclonal
Clone Number : PN0105

Antigen & Target Information

Specificity : This recombinant monoclonal antibody can detects endogenous levels of CD10 protein.
Gene name : Ms. EPN
Protein Name : Interleukin-3 receptor subunit alpha
Alias : IL3RA;IL3R;Interleukin-3 receptor subunit alpha;IL-3 receptor subunit alpha;IL-3R subunit alpha;IL-3R-alpha;IL-3RA;CD123

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL).This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL.This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region ofThis

Cell localization : Cell membrane; Single-pass type II membrane protein.

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