Signaling pathway

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CD371 (PN0288) Nb-FC recombinant antibody

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Article Number: PA0755
Delivery time: 现货
Price: 100ug/2200
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Target: CD74
Application: ELISA
Reactivity : Human

隐藏域元素占位

Detailed Information

Recommended dilution ratio : ELISA 1:5000-100000; Flow Cyt 1-2μg/Test
Compose : Phosphate-buffered solution
Source : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification process : Recombinant Expression and Affinity purified
Storage : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration : Please check the information on the tube
Clonality : Monoclonal
Clone Number : PN0273

Antigen & Target Information

Specificity : This recombinant monoclonal antibody can detects endogenous levels of CD74 protein.
Gene name : CD74 DHLAG
Protein Name : C-type lectin domain family 12 member A (C-type lectin-like molecule 1) (CLL-1) (Dendritic cell-associated lectin 2) (DCAL-2) (Myeloid inhibitory C-type lectin-like receptor) (MICL) (CD antigen CD371)
Alias : CLL1;MICL;CLL-1;DCAL-2;C-type lectin domain family 12 member A;CD371;CD371 nanobody;

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded byThis gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation.This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]

Cell localization : Cell membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane. Golgi apparatus, trans-Golgi network. Endosome. Lysosome. Transits through a number of intracellular compartments in the endocytic pathway. It can either undergo proteolysis or reach the cell membrane.; [Isoform p41]: Late endosome . Lysosome .

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