Signaling pathway

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NTCP2 rabbit pAb

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Article Number: PG5040
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: NTCP2
Application: World Bank
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 38 kDa
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : This antibody detects endogenous levels of NTCP2 at Human/Mouse/Rat
Gene name : SLC10A2 ASBT ISBT NTCP2
Protein Name : NTCP2

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010],

Cell localization : Membrane; Multi-pass membrane protein.

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