Signaling pathway

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CD36 (PTR1383) recombinant mouse mAb

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Article Number: PH0640
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: CD36
Application: Flow Cyt, ELISA
Reactivity : Human
MW(Observed) : 90 kD
Host Species: Mouse
Isotype : IgG1, Kappa

隐藏域元素占位

Detailed Information

Recommended dilution ratio : ELISA 1:5000-100000; Flow Cyt 1-2μg/Test
Compose : Phosphate-buffered solution
Purification process : Recombinant Expression and Affinity purified
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : Please check the information on the tube
Clonality : Monoclonal
Clone Number : PTR1383

Antigen & Target Information

Specificity : This recombinant monoclonal antibody can detects endogenous levels of CD36 protein.
Gene name : CD36
Protein Name : Platelet glycoprotein 4
Alias : CD36;GP3B;GP4;Platelet glycoprotein 4;Fatty acid translocase;FAT;Glycoprotein IIIb;GPIIIB;Leukocyte differentiation antigen CD36;PAS IV;PAS-4;Platelet collagen receptor;Platelet glycoprotein IV;GPIV;Thrombospondin receptor;CD36

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014],

Cell localization : Cell membrane ; Multi-pass membrane protein . Membrane raft . Golgi apparatus . Apical cell membrane . Upon ligand-binding, internalized through dynamin-dependent endocytosis. .

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