Signaling pathway

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AAT Monoclonal Antibody

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Article Number: PH1861
Delivery time: 一周
Price: 100 μL/2200
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Target: AAT
Application: WB, ELISA
Reactivity : Human,Mouse
MW(CalcμLated) : 47 kD
Host Species: Mouse

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : Affinity purification
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal

Antigen & Target Information

Specificity : AAT Monoclonal Antibody detects endogenous levels of AAT protein.
Gene name : SERPINA1
Protein Name : Alpha-1-antitrypsin
Alias : SERPINA1;AAT;PI;Alpha-1-antitrypsin;Alpha-1 protease inhibitor;Alpha-1-antiproteinase;Serpin A1

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],

Cell localization : Secreted. Endoplasmic reticulum. The S and Z allele are not secreted effectively and accumulate intracellularly in the endoplasmic reticulum.; [Short peptide from AAT]: Secreted, extracellular space, extracellular matrix.

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