Signaling pathway

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MAP3K2 rabbit pAb

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Article Number: PD0389
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: MAP3K2
Application: WB, ELISA
Reactivity : Human,Mouse
MW(CalcμLated) : 68 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:1000-2000; ELISA 1:5000-20000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : This antibody detects endogenous levels of Human MAP3K2
Gene name : MAP3K2 MAPKKK2 MEKK2
Protein Name : Mitogen-activated protein kinase kinase kinase 2
Alias : MEK kinase 2;MAP3K2;MAPKKK2;MEKK2;Mitogen-activated protein kinase kinase kinase 2;MAPK/ERK kinase kinase 2;MEKK 2

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasm . Nucleus . Upon EGF stimulation, translocates into the nucleus.

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