Signaling pathway

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CD79b (PTF0050) Mouse mAb

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Article Number: PR0114
Delivery time: 现货
Price: 100 μL/1500
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Target: CD79b
Application: FC,IF
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 26 kD
MW(Observed) : 24kD
Host Species: Mouse
Isotype : Mouse IgG1/Kappa

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:100-1:200;WB 1:2000-1:10000;IF 1:200-1:1000;FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application
Compose : PBS, pH 7.4
Purification process : Protein A
Storage : Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Clone Number : Monoclonal

Antigen & Target Information

Specificity : Endogenous
Gene name : CD79B B29 IGB
Protein Name : B-cell antigen receptor complex-associated protein beta chain (B-cell-specific glycoprotein B29) (Ig-beta) (Immunoglobulin-associated B29 protein) (CD antigen CD79b)
Alias : CD79B;B29;IGB;B-cell antigen receptor complex-associated protein beta chain;B-cell-specific glycoprotein B29;Ig-beta;Immunoglobulin-associated B29 protein;CD79b;CD79b nanobody;

Database connection:

Organism

Gene ID

SwissProt

Background:

The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor.This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Cell localization : Cell membrane; Single-pass type I membrane protein. Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts. .

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