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Signaling pathway
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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PH1157
Delivery time: 一周
Price: 100 μL/2200
Target： Hsp60
Application： WB,IF,IP
Reactivity ： Human,Mouse,Rat
MW(Observed) ： 60 kDa
Host Species： Mouse
隐藏域元素占位
Detailed Information
Recommended dilution ratio ： WB 1:1000; ICC 1:100; IP 1:100; IF 1:50-200
Compose ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process ： The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Storage ： -15°C to -25°C/1 year(Do not lower than -25°C
Clonality ： Monoclonal
Antigen & Target Information
Specificity ： This antibody detects endogenous levels of Hsp60 and does not cross-react with related proteins.
Gene name ： hsp60
Alias ： 60 kDa chaperonin; 60 kDa heat shock protein mitochondrial; 60 kDa heat shock protein, mitochondrial; CH60_HUMAN; Chaperonin 60; Chaperonin; Chaperonin, 60-KD; CPN 60; CPN60; fa04a05; GROEL; GroEL Homolog; Heat shock 60kD protein 1 chaperonin; Heat shock 60kDa protein 1; Heat shock protein 1; chaperonin; Heat Shock Protein 60; Heat shock protein 65; HLD4; Hsp 60; HSP 65; HSP-60; HSP60; HSP65; HSPD 1; HSPD1; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein; Short heat shock protein 60 Hsp60s1; Spastic paraplegia 13; SPG 13; SPG13.
Background：
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. [provided by RefSeq, Jun 2010],
Cell localization ： Mitochondrion matrix.
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Wuhan Pinofibio Biotechnology Co., Ltd.
Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
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