Signaling pathway

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Gab 1 (phospho Tyr307) Polyclonal Antibody

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Article Number: PF0850
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Gab 1
Application: IHC, IF, ELISA
Reactivity : Human,Mouse
MW(CalcμLated) : 77 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Modify-Modification : Phospho
Recommended dilution ratio : IHC 1:100-1:300; ELISA 1:40,000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Phospho-Gab 1 (Y307) Polyclonal Antibody detects endogenous levels of Gab 1 protein only when phosphorylated at Y307.
Gene name : GAB1
Protein Name : GRB2-associated-binding protein 1
Alias : GAB1; GRB2-associated-binding protein 1; GRB2-associated binder 1; Growth factor receptor bound protein 2-associated protein 1

Database connection:

Organism

Gene ID

SwissProt

Background:

GRB2-associated binding protein 1 (GAB1) Homo sapiens The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008],

Cell localization : cytosol,

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