Signaling pathway

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CD11b (PN0468) Nb-FC recombinant antibody

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Article Number: PA0675
Delivery time: 现货
Price: 100ug/2200
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Target: CD105
Application: ELISA
Reactivity : Human

隐藏域元素占位

Detailed Information

Recommended dilution ratio : ELISA 1:5000-100000
Compose : Phosphate-buffered solution
Source : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification process : Recombinant Expression and Affinity purified
Storage : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration : Please check the information on the tube
Clonality : Monoclonal
Clone Number : PN0372

Antigen & Target Information

Specificity : This recombinant monoclonal antibody can detects endogenous levels of CD105 protein.
Gene name : ENG END
Protein Name : Integrin alpha-M (CD11 antigen-like family member B) (CR-3 alpha chain) (Cell surface glycoprotein MAC-1 subunit alpha) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD antigen CD11b)
Alias : Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor; CD antigen CD11b;

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium.This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations inThis gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found forThis gene. [provided by RefSeq, May 2013]

Cell localization : Cell membrane ; Single-pass type I membrane protein .

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