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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PH0626
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target： CREBBP
Application： WB, IF, ELISA
Reactivity ： Human,
MW(CalcμLated) ： 266 kD
MW(Observed) ： 266 kD
Host Species： Mouse
Isotype ： IgG2b, Kappa
隐藏域元素占位
Detailed Information
Recommended dilution ratio ： WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Compose ： PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process ： Protein G
Storage ： -15°C to -25°C/1 year(Do not lower than -25°C
Concentration ： 1 mg/ml
Clonality ： Monoclonal
Clone Number ： PT0619
Antigen & Target Information
Specificity ： This antibody detects endogenous levels of CREBBP protein.
Gene name ： CREBBP CBP
Protein Name ： CREB-binding protein (EC 2.3.1.48)
Alias ： CREBBP;CBP;CREB-binding protein
Background：
CREB binding protein (CREBBP) Homo sapiens This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations invo
Cell localization ： Cytoplasmic, Nuclear
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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
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