Signaling pathway

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IFN-β Polyclonal Antibody

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Article Number: PD2149
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: IFN-β
Application: IHC, IF, ELISA
Reactivity : Human, Rat, Mouse,
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:50-200; ELISA 1:10,000-20,000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : The antibody detects endogenous IFN-β
Gene name : IFNB1 IFB IFNB
Protein Name : Interferon beta (IFN-beta) (Fibroblast interferon)
Alias : Interferon beta; IFN-beta; Fibroblast interferon;

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection. [provided by RefSeq, Sep 2015],

Cell localization : Secreted.

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