Signaling pathway

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ERK 1 (PTR1168) mouse mAb

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Article Number: PH0571
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: ERK 1
Application: WB, IF, ELISA
Reactivity : Human,Mouse,Rat,
MW(CalcμLated) : 43 kD
MW(Observed) : 44 kD
Host Species: Mouse
Isotype : IgG1, Kappa

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein G
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : PTR1168

Antigen & Target Information

Specificity : This antibody detects endogenous levels of ERK 1.
Gene name : MAPK3
Protein Name : Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (Microtubule-associated protein 2 kinase) (p44-ERK1)
Alias : ERK1;ERT2;ERK-1;PRKM3;P44ERK1;P44MAPK;HS44KDAP;HUMKER1A;p44-ERK1;p44-MAPK

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasmic, Nuclear

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