Signaling pathway

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Coronin 1A Polyclonal Antibody

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Article Number: PD6282
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Category:


Target: Coronin 1A
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 51 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Coronin 1A Polyclonal Antibody detects endogenous levels of Coronin 1A protein.
Gene name : CHORUS1A
Protein Name : Coronin-1A
Alias : CORO1A;CORO1;Coronin-1A;Coronin-like protein A;Clipin-A;Coronin-like protein p57;Tryptophan aspartate-containing coat protein;TACO

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16. [provided by RefSeq, Sep 2010],

Cell localization : Cytoplasm, cytoskeleton . Cytoplasm, cell cortex . Cytoplasmic vesicle, phagosome membrane . In non-infected macrophages, associated with the cortical microtubule network. In mycobacteria-infected macrophages, becomes progressively relocalized and retained around the mycobacterial phagosomes. Retention on the phagosomal membrane is strictly dependent on mycobacterial viability and not due to impaired acidification (By similarity). .

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