Signaling pathway

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Tryptase-3 Polyclonal Antibody

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Article Number: PD2296
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Category:


Target: Tryptase-3
Application: WB, ELISA
Reactivity : Human
MW(Observed) : 26 kD
Host Species: Rabbit
Isotype : IgG

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Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:10000-20000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Tryptase-3 Polyclonal Antibody detects endogenous levels of Tryptase-3
Gene name : TPSD1
Protein Name : Tryptase-3
Alias : Tryptase delta;Delta-tryptase;HmMCP-3-like tryptase III;Mast cell mMCP-7-like;Tryptase-3;

Database connection:

Organism

Gene ID

SwissProt

Background:

tryptase delta 1(TPSD1) Homo sapiens Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. Although this gene may be an exception, most of the tryptase genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and

Cell localization : Secreted . Released from the secretory granules upon mast cell activation. .

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