Signaling pathway

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NU214 Polyclonal Antibody

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Article Number: PG7718
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: NU214
Application: WB, ELISA
Reactivity : Human,Mouse
MW(Observed) : 229 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:5000-20000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : NU214 Polyclonal Antibody detects endogenous levels of protein.
Gene name : NUP214 CAIN CAN KIAA0023
Protein Name : Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN)

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

nucleoporin 214(NUP214) Homo sapiens The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene is a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is localized to the cytoplasmic face of the nuclear pore complex where it is required for proper cell cycle progression and nucleocytoplasmic transport. The 3' portion of this gene forms a fusion gene with the DEK gene on chromosome 6 in a t(6,9) translocation associated with acute myeloid leukemia and myelodysplastic syndrome. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015],

Cell localization : Nucleus, nuclear pore complex . Cytoplasmic side of the nuclear pore complex. .

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