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Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
Article Number: PH0597
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
Category:
Target： LAP
Application： IHC, WB, IF, ELISA
Reactivity ： Human,Mouse,Rat,
MW(CalcμLated) ： 48 kD
MW(Observed) ： 44 kD
Host Species： Mouse
Isotype ： IgG2b, Kappa
隐藏域元素占位
Detailed Information
Recommended dilution ratio ： IHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Compose ： PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process ： Protein G
Storage ： -15°C to -25°C/1 year(Do not lower than -25°C
Clonality ： Monoclonal
Clone Number ： PT2173
Antigen & Target Information
Specificity ： This antibody detects endogenous levels of TGF β1 protein.
Gene name ： TGFB1 TGFB
Protein Name ： Transforming growth factor beta-1 (TGF-beta-1) [Cleaved into: Latency-associated peptide (LAP)]
Alias ： Transforming growth factor beta-1; TGF-beta-1; [Cleaved into: Latency-associated peptide; LAP;]
Database connection:
Background：
transforming growth factor beta 1(TGFB1) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene i
Cell localization ： Cytoplasmic
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Wuhan Pinofibio Biotechnology Co., Ltd.
Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510
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