Signaling pathway

Contact Us

15392937510

Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510

Image Name

MLK3 (Phospho Thr277+Ser281) rabbit pAb

Copy

Download
Article Number: PF0378
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
+


Target: MLK3
Application: WB, ELISA, IHC
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 93 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Modify-Modification : Phospho
Recommended dilution ratio : WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : This antibody detects endogenous levels of Human,Mouse,Rat MLK3 (Phospho Thr277+Ser281)
Gene name : MAP3K11 MLK3 PTK1 SPRK
Protein Name : MLK3 (Phospho Thr277+Ser281)
Alias : Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase;

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Location is cell cycle dependent.

Recommended

Relevant Literature

Leave a message for inquiry

Please leave your inquiry, and we will contact you as soon as possible.

Submit