Signaling pathway

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c-Rel Monoclonal Antibody

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Article Number: PH1747
Delivery time: 一周
Price: 100 μL/2200
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Target: c-Rel
Application: WB, IF, ELISA
Reactivity : Human,Mouse
MW(CalcμLated) : 69 kDa
Host Species: Mouse

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : Affinity purification
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal

Antigen & Target Information

Specificity : c-Rel Monoclonal Antibody detects endogenous levels of c-Rel protein.
Gene name : REL
Protein Name : Proto-oncogene c-Rel
Alias : REL;Proto-oncogene c-Rel

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014],

Cell localization : Nucleus .

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