Signaling pathway

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CD62P (PN0636) Nb-FC recombinant antibody

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Article Number: PA0413
Delivery time: 现货
Price: 100ug/2200
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Target: CD44
Application: ELISA
Reactivity : Human

隐藏域元素占位

Detailed Information

Recommended dilution ratio : ELISA 1:5000-100000
Compose : Phosphate-buffered solution
Source : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification process : Recombinant Expression and Affinity purified
Storage : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration : Please check the information on the tube
Clonality : Monoclonal
Clone Number : PN0027

Antigen & Target Information

Specificity : This recombinant monoclonal antibody can detects endogenous levels of CD44 protein.
Gene name : CD44 LHR MDU2 MDU3 MIC4
Protein Name : P-selectin (CD62 antigen-like family member P) (Granule membrane protein 140) (GMP-140) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (Platelet activation dependent granule-external membrane protein) (PADGEM) (CD antigen CD62P)
Alias : CD62;GRMP;PSEL;CD62P;GMP140;LECAM3;PADGEM;CD62P nanobody;

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded byThis gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs).This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts forThis gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity ofThis protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]

Cell localization : Cell membrane ; Single-pass type I membrane protein . Cell projection, microvillus . Colocalizes with actin in membrane protrusions at wounding edges. Co-localizes with RDX, EZR and MSN in microvilli. Localizes to cholesterol-rich membrane-bound lipid raft domains. .

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