Signaling pathway

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CD3 (PTR1374) recombinant mouse mAb

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Article Number: PH0498
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560

Detailed Information

Recommended dilution ratio : ELISA 1:5000-100000; Flow Cyt 1-2μg/Test
Compose : Phosphate-buffered solution
Purification process : Recombinant Expression and Affinity purified
Storage : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration : Please check the information on the tube
Clonality : Monoclonal
Clone Number : PTR1374

Antigen & Target Information

Specificity : This recombinant monoclonal antibody can detects endogenous levels of CD3 protein.
Gene name : CD3E T3E
Protein Name : T-cell surface glycoprotein CD3 epsilon chain (T-cell surface antigen T3/Leu-4 epsilon chain) (CD antigen CD3e)
Alias : T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD antigen CD3e; CD3 nanobody;

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded byThis gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex.This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects inThis gene cause immunodeficiency.This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

Cell localization : Cell membrane ; Single-pass type I membrane protein .

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