Signaling pathway

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JAK2/3 (Phospho Tyr966/939) Antibody

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Article Number: PF0706
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560

Detailed Information

Modify-Modification : Phospho
Recommended dilution ratio : WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : This antibody detects endogenous levels of JAK2/3 (Phospho-Tyr966/939) Antibody at Human:Y966/939;Mouse:Y966/935;Rat:Y966/935, It doesn't reacte with total protein.
Gene name : JAK2 JAK3
Protein Name : JAK2/3
Alias : Tyrosine-protein kinase JAK2/JAK3;Janus kinase 2/Janus kinase 3;JAK-2/JAK-3;

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. [provided by RefSeq, Jul 2008],

Cell localization : Endomembrane system ; Peripheral membrane protein . Cytoplasm . Nucleus .

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