Signaling pathway

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Collagen Type II (ABT163) mouse mAb

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Article Number: PH0346
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Collagen II
Application: IHC, WB, IF, ELISA
Reactivity : Human,
MW(CalcμLated) : 141 kD
MW(Observed) : 200 kD
Host Species: Mouse
Isotype : IgG1, Kappa

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : Protein G
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Clone Number : ABT163

Antigen & Target Information

Specificity : The antibody can specifically recognize human Collagen Type II protein, collagen types I, III, IV and V do not respond to the anbody.
Gene name : COL2A1
Protein Name : Collagen Type II
Alias : Collagen alpha-1;II;chain;Alpha-1 type II collagen;[Cleaved into: Collagen alpha-1;II;chain;Chondrocalcin]

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008],

Cell localization : Cytoplasmic

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