Signaling pathway

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ETBR Polyclonal Antibody

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Article Number: PD2288
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: ETBR
Application: WB, IHC, IF, ELISA
Reactivity : Human, Rat, Mouse,
MW(Observed) : 50 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC: 100-300; WB 1:500-2000; ELISA 1:10000-20000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : ETBR Polyclonal Antibody detects endogenous levels of ETBR
Gene name : EDNRB
Protein Name : Endothelin B receptor (ET-B) (ET-BR) (Endothelin receptor non-selective type)
Alias : Endothelin B receptor; ET-B; ET-BR; Endothelin receptor non-selective type;

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016],

Cell localization : Cell membrane; Multi-pass membrane protein. internalized after activation by endothelins. .

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