Signaling pathway

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AChRβ1 Polyclonal Antibody

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Article Number: PD7122
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: AChRβ1
Application: WB, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 55 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : AChRβ1 Polyclonal Antibody detects endogenous levels of AChRβ1 protein.
Gene name : CHRNB1
Protein Name : Acetylcholine receptor subunit beta
Alias : CHRNB1;ACHRB;CHRNB;Acetylcholine receptor subunit beta

Database connection:

Organism

Gene ID

SwissProt

Background:

The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008],

Cell localization : Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

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