Signaling pathway

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P4K2A Polyclonal Antibody

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Article Number: PG7670
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: P4K2A
Application: WB, ELISA
Reactivity : Human, Rat, Mouse
MW(Observed) : 52 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:5000-20000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : P4K2A Polyclonal Antibody detects endogenous levels of protein.
Gene name : PI4K2A
Protein Name : Phosphatidylinositol 4-kinase type 2-alpha (Phosphatidylinositol 4-kinase type II-alpha)

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs (Barylko et al., 2001 [PubMed 11244087]).[supplied by OMIM, Mar 2008],

Cell localization : Golgi apparatus, trans-Golgi network membrane ; Lipid-anchor . Membrane raft . Cell projection, dendrite . Cell junction, synapse, presynaptic cell membrane . Cell junction, synapse, synaptosome . Mitochondrion . Endosome . Cytoplasmic vesicle . Membrane ; Lipid-anchor . Cell membrane . Perikaryon . Cell projection, neuron projection . Found in subdomains of the plasma membrane termed non-caveolar membrane rafts. Transported from neuronal cell body to neuron projections and neurite tips in a BLOC-1- and AP-3-complexes-dependent manner. .

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