Signaling pathway

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Cytokeratin (Pan) Monoclonal Antibody

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Article Number: PH1731
Delivery time: 一周
Price: 100 μL/2200
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Target: Cytokeratin (Pan)
Application: IHC, IF, ELISA
Reactivity : Human
Host Species: Mouse

隐藏域元素占位

Detailed Information

Recommended dilution ratio : IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : Affinity purification
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal

Antigen & Target Information

Specificity : Cytokeratin (Pan) Monoclonal Antibody detects endogenous levels of Cytokeratin (Pan) protein.
Gene name : KRT5
Protein Name : Keratin type II cytoskeletal 5
Alias : KRT5; Keratin; type II cytoskeletal 5; 58 kDa cytokeratin; Cytokeratin-5; CK-5; Keratin-5; K5; Type-II keratin Kb5

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

keratin 5(KRT5) Homo sapiens The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],

Cell localization : nucleus, cytoplasm, mitochondrion, cytosol, intermediate filament, plasma membrane, membrane, keratin filament, extracellular exosome,

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