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Article Number: PH1811
Delivery time: 一周
Price: 100 μL/2200
Category:
Target: BMP-4
Application: WB, ELISA
Reactivity : Human
MW(CalcμLated) : 47 kD
Host Species: Mouse
隐藏域元素占位
Detailed Information
Recommended dilution ratio : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : Affinity purification
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Clonality : Monoclonal
Antigen & Target Information
Specificity : BMP-4 Monoclonal Antibody detects endogenous levels of BMP-4 protein.
Gene name : BMP4
Protein Name : Bone morphogenetic protein 4
Alias : BMP4;BMP2B;DVR4;Bone morphogenetic protein 4;BMP-4;Bone morphogenetic protein 2B;BMP-2B
Background:
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. [provided by RefSeq, Jul 2016],


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