Signaling pathway

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CD90 (PN0412) Nb-FC recombinant antibody

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货号: PA0637
货期: 现货
价格: 100ug/2200

Detailed Information

推荐稀释比 : ELISA 1:5000-100000
组成 : Phosphate-buffered solution
来源 : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
纯化工艺 : Recombinant Expression and Affinity purified
储存 : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
浓度 : Please check the information on the tube
克隆性 : Monoclonal
克隆号 : PN0102

Antigen & Target Information

特异性 : This recombinant monoclonal antibody can detects endogenous levels of CD68 protein.
基因名称 : CD68
蛋白名称 : Thy-1 membrane glycoprotein (CDw90) (Thy-1 antigen) (CD antigen CD90)
别名 : THY1; Thy-1 membrane glycoprotein; CDw90; Thy-1 antigen; CD antigen CD90; CD90 nanobody;

Database connection:

Organism

Gene ID

SwissProt

背景:

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008]

细胞定位 : [Isoform Short]: Cell membrane; Single-pass type I membrane protein.; [Isoform Long]: Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein.

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