Signaling pathway

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CD366 (PN0210) Nb-FC recombinant antibody

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Article Number: PA0464
Delivery time: 两个月
Price: 100ug/2200

Detailed Information

Recommended dilution ratio : ELISA 1:5000-100000
Compose : Phosphate-buffered solution
Source : Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
Purification process : Recombinant Expression and Affinity purified
Storage : -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
Concentration : Please check the information on the tube
Clonality : Monoclonal
Clone Number : PN0502

Antigen & Target Information

Specificity : This recombinant monoclonal antibody can detects endogenous levels of CD117 protein.
Gene name : KIT SCFR
Protein Name : Hepatitis A virus cellular receptor 2 (HAVcr-2) (T-cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T-cell immunoglobulin mucin receptor 3) (TIM-3) (T-cell membrane protein 3) (CD antigen CD366)
Alias : TIM3;CD366;KIM-3;SPTCL;TIMD3;Tim-3;TIMD-3;HAVcr-2;CD366 nanobody;TIM-3 nanobody;

Database connection:

Organism

Gene ID

SwissProt

Background:

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit.This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations inThis gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found forThis gene. [provided by RefSeq, Jul 2008]

Cell localization : [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Cytoplasm . Detected in the cytoplasm of spermatozoa, especially in the equatorial and subacrosomal region of the sperm head. .

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