Signaling pathway

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ROBO1 Polyclonal Antibody

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Article Number: PG7470
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: ROBO1
Application: WB, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 181 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:5000-20000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : ROBO1 Polyclonal Antibody detects endogenous levels of protein.
Gene name : ROBO1 DUTT1
Protein Name : Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1)

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],

Cell localization : Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Endoplasmic reticulum–Golgi intermediate compartment membrane; Single-pass membrane protein. Detected at growth cones in thalamus neurons. Detected at growth cones in thalamus neurons (By similarity). PRRG4 prevents cell surface location and both colocalize in the Endoplasmic reticulum/Golgi adjacent to the cell nucleus (By similarity). .

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