Signaling pathway

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Dok-2 (phospho Tyr345) Polyclonal Antibody

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Article Number: PF0805
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: Dok-2
Application: IHC, IF, ELISA
Reactivity : Human,Mouse
MW(CalcμLated) : 45 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Modify-Modification : Phospho
Recommended dilution ratio : IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : Phospho-Dok-2 (Y345) Polyclonal Antibody detects endogenous levels of Dok-2 protein only when phosphorylated at Y345.
Gene name : DOK2
Protein Name : Docking protein 2
Alias : DOK2;Docking protein 2;Downstream of tyrosine kinase 2;p56;dok-2;

Database connection:

Organism

Gene ID

SwissProt

Background:

docking protein 2(DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008],

Cell localization : cytosol,

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