Signaling pathway

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SRGP2 rabbit pAb

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Article Number: PD1310
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: SRGP2
Application: World Bank
Reactivity : Human,Mouse,Rat
MW(CalcμLated) : 118 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : This antibody detects endogenous levels of SRGP2 at Human/Mouse/Rat
Gene name : SRGAP2 ARHGAP34 FNBP2 KIAA0456 SRGAP2A
Protein Name : SRGP2

Database connection:

Organism

Gene ID

SwissProt

Background:

This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014],

Cell localization : Cell membrane . Cell projection, dendritic spine . Cell junction, synapse, postsynaptic density . Cell junction, synapse, postsynaptic cell membrane . Cell projection, lamellipodium . Cytoplasmic vesicle, phagosome . Nucleus . Cytoplasm, cytosol . Recruited to actin-rich phagosomes during phagocytosis (By similarity). Translocates from nucleus to cytoplasm during development (By similarity). .

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