Signaling pathway

Contact Us

15392937510

Address: 14th Floor, Building A, Wuhan Guoying Seed Industry Building, No. 666, Shendun Fourth Road, Jiangxia District, Wuhan, Hubei Province
Email: pinuofei2017@163.com
TEL: 15392937510

Image Name

GPVI Polyclonal Antibody

Copy

Download
Article Number: PG6613
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
+


Target: GPVI
Application: WB, ELISA
Reactivity : Human,Mouse
MW(Observed) : 55 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-2000; ELISA 1:5000-20000
Compose : PBS, 50% glycerol, 0.05% Proclin 300, 0.05% BSA
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : GPVI Polyclonal Antibody detects endogenous levels of protein.
Gene name : GP6
Protein Name : Platelet glycoprotein VI (GPVI) (Glycoprotein 6)

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],

Cell localization : [Isoform 1]: Cell membrane; Single-pass membrane protein.; [Isoform 2]: Cell membrane; Single-pass membrane protein.

Recommended

Relevant Literature

Leave a message for inquiry

Please leave your inquiry, and we will contact you as soon as possible.

Submit