Signaling pathway

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IFN-αR2 Polyclonal Antibody

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Article Number: PD2629
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; IF 1:50-200
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : IFN-αR2 Polyclonal Antibody detects endogenous levels of IFN-αR2 protein.
Gene name : IFNAR2
Protein Name : Interferon alpha/beta receptor 2
Alias : IFNAR2;IFNABR;IFNARB;Interferon alpha/beta receptor 2;IFN-R-2;IFN-alpha binding protein;IFN-alpha/beta receptor 2;Interferon alpha binding protein;Type I interferon receptor 2

Database connection:

Organism

Gene ID

SwissProt

Mouse
Background:

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Cell localization : [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted.

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