Signaling pathway

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SR-1B Polyclonal Antibody

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Article Number: PD3477
Delivery time: 现货
Price: 50 μL/960; 100 μL/1600; 200 μL/2560
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Target: SR-1B
Application: WB, IHC, IF, ELISA
Reactivity : Human,Mouse,Rat
MW(Observed) : 43 kD
Host Species: Rabbit
Isotype : IgG

隐藏域元素占位

Detailed Information

Recommended dilution ratio : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Compose : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification process : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage : -15°C to -25°C/1 year(Do not lower than -25°C
Concentration : 1 mg/ml
Clonality : Polyclonal

Antigen & Target Information

Specificity : SR-1B Polyclonal Antibody detects endogenous levels of SR-1B protein.
Gene name : HTR1B
Protein Name : 5-hydroxytryptamine receptor 1B
Alias : HTR1B;HTR1DB;5-hydroxytryptamine receptor 1B;5-HT-1B;5-HT1B;S12;Serotonin 1D beta receptor;5-HT-1D-beta;Serotonin receptor 1B

Database connection:

Organism

Gene ID

SwissProt

Background:

The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs. [provided by RefSeq, Nov 2015],

Cell localization : Cell membrane ; Multi-pass membrane protein .

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